Oral Systemic Health Connection: What Your Gums Reveal
Research has explored the oral systemic health connection between gum disease and cardiovascular, metabolic, and other conditions. Here's what the science actually says.
Read article →✦ Free shipping on all orders+1 FREE tube — first 1,000 orders · Free shipping on every order
The harmful strains it misses are now being studied for links to Alzheimer's, heart disease, and IBS. DENT-TASTIC was formulated by a PhD orthodontics professor to help target the bad bacteria — and leave the good.

The Problem
Most toothpaste foams, freshens, and scrubs — then stops. It was never built to target the harmful oral bacteria that published research now links to Alzheimer's, cardiovascular disease, and IBS. Worse, the broad-spectrum agents in mainstream formulas strip out the beneficial bacteria your mouth needs to stay balanced — leaving you with clean teeth and an unprotected mouth.
The Science
The bacteria don't stay in your mouth.

The Solution
DENT-TASTIC was developed by Professor Bakr Rabie — a PhD orthodontics scientist with over three decades of published research into oral health and the microbiome. Its patented natural active ingredients, Paeoniflorin and Quercetin, are formulated to help target the harmful oral bacteria studied for links to systemic disease — while leaving the beneficial bacteria your mouth depends on intact.

Prof. Bakr Rabie
PhD · Northwestern University
Globally published. Award-winning. The scientist behind the formula.
View Research →
The Product
DENT-TASTIC Fresh Mint Toothpaste
100g · SKU: DT-FM-100
Each tube valued at $6.25
Bundle into a protocol from $2.50/tube — up to 60% less than buying singles
Formulated with patented natural active ingredients — Paeoniflorin and Quercetin — to help target harmful oral bacteria and support gum health. SLS-free · Triclosan-free · Microbiome-aware.
The Method
One tube, one month. Choose a protocol — the more you commit, the more you save.

Reset Protocol
3 tubes · 3 months
$4.69 per tube
Free shipping on every order

Restoration Protocol
6 tubes · 6 months
$3.50 per tube incl. bonus
Free shipping on every order

Lifetime Protocol
12 tubes · 1 year
$2.50 per tube incl. bonus
Free shipping on every order
Why six months? The duration Prof. Rabie's research suggests for the formula to work through a full oral renewal cycle.
Two patented natural active ingredients — each chosen for their studied role in oral microbiome health.
Paeoniflorin and Quercetin — studied for their role in targeted oral health support.

Natural Active · Plant Extract
Derived from Paeonia lactiflora peony root, paeoniflorin is a water-soluble bioactive compound studied in human gingival fibroblast cultures for its effect on inflammation markers linked to gum health. Published research suggests it may help support gum-tissue integrity by modulating MMP-8 activity[1] and has been studied for its anti-inflammatory action in oral tissue[2].
*Based on in vitro research. Educational only — DENT-TASTIC is not intended to diagnose, treat, cure, or prevent any disease.

Natural Active · Flavonoid
A plant-derived flavonoid found in many fruits and vegetables. In research co-authored by DENT-TASTIC founder Prof. Bakr Rabie, quercetin was shown to help target gram-negative oral bacteria and support gum health[4].
*Based on in vitro research. Educational only — DENT-TASTIC is not intended to diagnose, treat, cure, or prevent any disease.
DENT-TASTIC didn't invent its actives — it formulated them. What follows is the foundation of the tube.
Research has explored the oral systemic health connection between gum disease and cardiovascular, metabolic, and other conditions. Here's what the science actually says.
Read article →Found in apples, onions, and tea — now studied for what it does inside the mouth.
Read article →A short read on what the patent actually claims, and what it deliberately does not.
Read article →The Science
Peer-reviewed studies behind the active ingredients in DENT-TASTIC. Provided for education only — see the disclaimer below.
Filatov V, et al. (2025). Novel prospectives of Paeonia lactiflora root extract as a natural modulator of LPS-induced inflammation and collagen I synthesis in skin and oral gingival cells. Frontiers in Natural Products. doi:10.3389/fntpr.2025.1625451
Studied Paeonia lactiflora extract directly in human oral gingival fibroblasts — its effect on the inflammation marker MMP-8 and on type I collagen is the closest evidence to how paeoniflorin behaves in the mouth.
Yu F, Xu N, Zhou Y, et al. (2019). Anti-inflammatory effect of paeoniflorin combined with baicalin in oral inflammatory diseases. Oral Diseases. View study
Examined paeoniflorin’s anti-inflammatory activity in oral tissue and human oral keratinocytes, supporting its role in calming oral inflammation.
Choi Y-R, Kang M-K (2022). Evaluation of Cytotoxic and Antibacterial Effect of Methanolic Extract of Paeonia lactiflora. Medicina (Kaunas). View study
Found Paeonia lactiflora extract active against Streptococcus mutans, a primary driver of tooth decay.
Geoghegan F, Wong RWK, Rabie ABM (2010). Inhibitory effect of quercetin on periodontal pathogens in vitro. Phytotherapy Research. View study
Co-authored by DENT-TASTIC founder Prof. Bakr Rabie; showed quercetin inhibits periodontal (gum-disease) pathogens in vitro.
*Based on in vitro research. Educational only — DENT-TASTIC is not intended to diagnose, treat, cure, or prevent any disease.
Refers to published peer-reviewed research on associations between oral bacteria and systemic health conditions. Educational only — DENT-TASTIC is not intended to diagnose, treat, cure, or prevent any disease.
DENT — TASTIC
Fresh Mint · 100g